We’ve all heard the expression, “no pain, no gain.” But Trumbull, Conn.-based ultra- sound device company ZetrOZ Inc., is finding success by playing with the old adage a bit, more
along the lines of“gain via the pursuit of no pain.”The
no-pain part of the equation comes in the form of the
company’s sustained acoustic medicine device, simply
dubbed SAM by the technology’s developers.
SAM, according to the company, is the first and
only multiple-hour bio-electronic wearable device for
pain and accelerated healing. The device was created
to address the growing demand for non-pharmaceutical and bio-regenerative alternatives to typical
pharmaceutical-based pain treatments in the approximately $62 billion U.S. pain management market.
The technology received U.S. Food and Drug
Administration (FDA) 510(k) clearance and was CE
marked early in 2014 and is available for daily use in
ZetrOZ officials have described SAM as a “new
weapon in the fight against arthritis and back pain.”
In recent months, good news has followed the small
startup device company, which was founded in 2009.
SAM marked successful clinical trials supported by the National Institutes of Health for treating knee arthritis, upper back
and tendonitis pain, and currently is in testing by the National
Space Biomedical Research Institute for use on astronauts—on
the ground and in space. The company also has reported positive results with elite Olympic athletes, including triathlete Sarah
Crane and runner Diane Stokes.
In Canada and Europe, SAM is cleared for healing soft tissue,
but not yet in the United States.
The technology also had its international debut during last fall’s
Medica trade fair in Düsseldorf, Germany, which provided hospitals and medical device distributors outside the United States with
the opportunity to demo and purchase SAM as well as meet with
the biomedical scientist behind the technology, ZetrOZ inventor
and Chief Scientific Officer George K. Lewis, Ph.D.
“SAM brings first-line therapy to acute pain sufferers before
that pain becomes chronic,” said Lewis, who started ZetrOZ be-
fore he turned 30. “We are working to manage pain and resolve
medical conditions for the 1.5 billion sufferers worldwide by in-
troducing doctors, physical therapists and hospitals to sustained
Since its U.S. introduction, SAM has been adopted by phys-
iotherapists, athletic trainers, sports medicine specialists, and
orthopedists who have documented measurable improvement
in mobility, range of motion and overall health outcomes with a
wide spectrum of patients, according to the company.
Maintaining such rapid forward momentum in the medical
technology sector, however, takes cash, along with a lot of patience and ingenuity.
“We’ve been very creative with our funding,” Lewis told
Orthopedic Design & Technology. “We’ve brought a lot of resources together.”
An Idea That’s Ultra-Sound
A Connecticut-based startup is changing the way patients and
physicians use ultrasound.
Christopher Delporte • Editorial Director
The name’s SAM: A multiple-hour, bio-electronic wearable ultrasound device for pain
and accelerated healing. Photo courtesy of ZetrOZ Inc.